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Sinead O'Connor's mental illness has gotten out of control ... and we're told family members are starting to feel there's nothing that can be done to save her.

Sources close to the situation tell us O'Connor's family has spent decades trying to get the singer professional help -- we're told the problem is she doesn't want to get help. The source says her family is trying to move on with their lives now after years of emotional abuse, fleeing and blaming her children for her suicide attempts.

However, we're told a family member did step in when O'Connor went missing.

We're told O'Connor had been sending voicemails and texts to a relative threatening to kill herself -- hours later that relative stepped in when they were contacted by O'Connor's friend she's staying with, saying she'd gone missing.

Chris Brown got thrown off a private jet for allegedly hotboxing the aircraft.

TMZ obtained a Miami-Dade police report which says cops were called to the Signature Aviation at Miami International Airport Monday after Brown's pilot complained he smelled a strong odor of marijuana coming from the cabin.

We're told the pilot had warned Brown and his entourage not to light up on the aircraft, but they ignored him even before the plane pushed back.

When cops arrived they smelled it too, and kicked all passengers off the aircraft. No one was arrested.

Brown's friends were arrogant about the ordeal, chronicling everything on Snapchat.

Here's Conor McGregor BOXING -- trading shots with a former IBO champion at a prestigious L.A. boxing gym ... and TMZ Sports has the footage.

It all went down at Box 'N Burn gym in Brentwood -- when the UFC superstar stepped in the ring with former IBO welterweight champ Chris van Heerden to see if he could hang.

Donald Trump says his fans can deliver a nasty tweet like nobody else ... especially when directed at Megyn Kelly.

The Donald sat down with the Fox anchor and made it clear ... his supporters come out guns a blazing when he's embroiled in a feud. Megyn called Donald out on retweeting some of the more aggressive posts aimed at her, to which Donald replied he knew she's been called MUCH worse.

Master P will not be collecting his reality show payday ... instead the entire lump sum of nearly a million bucks will go directly to his longtime estranged wife.

The judge in their ongoing war over child and spousal support ordered Master P to hand over $825,000 -- his salary for Season 2 of "Master P's Family Empire" -- to Sonya Miller. According to docs, that amount will cover back child and spousal support payments. The judge said the amount will also be used to secure future support.

As we've reported ... Sonya's been griping for years that P refused to give her a cent in support -- even though she was with him when he built his No Limit fortune, now estimated at $200 million.

The judge's order also requires him to pay $15k to Sonya's lawyer.

Jillian Michaels has a real issue with her neighbor's pooches ... and it's gotten so bad she's called in the big guns to fix it.

Law enforcement sources tell TMZ Jillian's been in a fight with her Malibu next-door neighbor for months. We're told Jillian recently filed a complaint with animal control, saying the neighbor's dogs are a total menace ... charging her fence, bothering her dogs and scaring her kids and horses too.

Animal control made a visit to Jillian's place last month but didn't see any cause for concern. They also checked the fence line for any breaks, but saw no problem.

"Weird Al" Yankovic has some parodies of Prince hits stashed away in his vault, but they'll never see the light of day.

Prince had a storied history of refusing Weird Al's requests to rework his music, so when we got Al at LAX, we asked him if there was a chance he'd now get approval from Prince's family ... or even the estate.

Check out his reply -- you won't be hearing any knockoffs like "Little Red Fiat" or "Raspberry Toupée" ... but the reason why is what's really interesting.

Mr. T was pure gold bullying tightrope walker Nik Wallenda, but the tables quickly turned on T himself when he was challenged to take the wire.

The pair was in NYC on Tuesday for Fairfield Inn & Suites National Amazing Month as the pop culture icons went head to head, so to speak.

Check out the vid, the world's best balancer attempts crossing a high-wire while Mr. T barks relentlessly.

4:30 PM PT -- Kesha now denies she was going to take a shot at Dr. Luke at the BMAs ... insisting she was merely going to perform a tribute to Bob Dylan by singing a cover of his, "It Ain't Me, Babe."

She says she was never going to "allude to my legal situation in any way. I simply wanted to sing a song I love to honor an artist I have always looked up to."

Production sources on the award show tell us the Dylan classic includes several lines that could easily refer to Kesha's situation with Luke ... and that was not a coincidence.

Dr. Luke is putting the kibosh on Kesha performing at the Billboard Music Awards ... where she was planning to make a "statement" about her war with Luke and Sony.

A rep for Dick Clark Productions -- which is producing the award show on Sunday -- says Dr. Luke's label, Kemosabe Records, has been unable to reach an agreement with Kesha for her to take the stage.

TMZ broke the story ... production sources told us the singer was going to reference her epic legal battle during her live BMAs performance. Problem for her is Kemosabe holds all the power, since it still controls her music rights.

We're told Dr. Luke had signed off, but pulled the plug once he got wind of what Kesha was planning.

There's an eerie 'Sopranos' coincidence surrounding James Gandolfini and the paramedic on trial for stealing his Rolex the day he died.

The paramedic, whose trial started Monday in Rome, is Claudio Bevilacqua. That name might sound familiar to hardcore 'Sopranos' fans ... since Tony offed a Matt Bevilaqua in a 2001 episode of HBO's hit show.

On the show, Bevilaqua robbed Tony's crew and demanded a watch from one of the guys. The boss eventually catches up with Bevilaqua and delivers some mob justice.

Adding to the creepy life imitating art thing -- Bevilaqua was played by Lillo Brancato, who eventually did time in real life for attempted burglary.

The whole thing is just weird. Check out the TV heist.

Arnold Schwarzenegger's youngest son can EASILY revive "Conan the Barbarian" if Hollywood comes callin' ... just hand the kid a sword.

Joseph Baena was tossing the pigskin, shirtless on the beach in Malibu -- and the 18-year-old college student unintentionally struck a lot of the poses his father did back in the '80s.

Alanis Morissette has just made good on her threat ... suing her former business managers for allegedly stealing more than $4.7 million.

TMZ broke the story ... the business management company -- GSO -- filed suit Monday against one of their own partners ... Jonathan Schwartz, who also reps Beyonce and Mariah Carey. GSO admits Alanis was threatening to sue the company because Schwartz went rogue and allegedly stole the loot.

Alanis claims in her lawsuit ... there was a "pattern of wrongful conduct" by Schwartz and GSO. She said her plan when she hired them back in 2007 ... not to spend any of the money but instead to live off the interest.

She says $8 million was wrongfully transferred from her investment accounts, and millions disappeared.

Tom Cruise has decided to leave Los Angeles because he's saying goodbye to the estate he called home for nearly a decade.

Our real estate spies tell us ... Tom has sold the 10,000 square foot mansion he shared with Katie Holmes for $40 million. He was asking $45 mil but no takers at that price. Tom still cashed in ... he bought the pad from real estate guru Kurt Rappaport -- who owed it back in 2007 -- for $32.5 mil.

The buyer is billionaire Leon Black, who's worth $4.7 billion. Black owns a private equity firm.

As for the house, it has 7 bedrooms, 9 bathrooms, a tennis court, a swimming pool (of course), a children's playground and a couple of guesthouses.

The house is currently in escrow. Tom also sold a Hollywood Hills compound back in October for $11.4 million to Eva Longoria.

We don't know where Tom's gonna call home.

Jay Z and Beyonce got outbid again in their search for an L.A. home ... this time designer/director Tom Ford beat them out.

Our real estate sources tell us ... Tom offered $50 million on a Beverly Hills mansion ... he edged out Jay and Bey, who bid $49 mil.

The estate is awesome ... 14,000 square feet, sitting on 3.2 acres and has 9 bedrooms, and 10 bathrooms. It was built in 1934 and owned by the rich and famous, including actor William Powell and 'James Bond' producer Albert Broccoli. The house is in escrow.

And how's this ... Jay Z has a song titled "Tom Ford" where he hypes up the brand.

You'll recall Jay Z and Beyonce lost out on another home back in 2014 ... the one purchased by Minecraft creator Markus Persson.